Influenza evolution navigates stability valleys
نویسندگان
چکیده
By reconstructing how an influenza protein collected in 1968 might have evolved into one collected in 2007, researchers have obtained new insights into the interactions between genetic mutations.
منابع مشابه
Complexity in the immune system
The immune system is a real-time example of an evolving system that navigates the essentially infinite complexity of protein sequence space. How this system responds to disease and vaccination is discussed. Of particular focus is the case when vaccination leads to increased susceptibility to disease, a phenomenon termed original antigenic sin. A physical theory of protein evolution to explain l...
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